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There are several matches for 'toxin transporter'.
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409 matches
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organism
protein
1)
Homo sapiens
USP6NL - USP6 N-terminal-like protein; Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde
transport
from the endocytic pathway to the Golgi apparatus. Involved in the
transport
of Shiga
toxin
from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.
[a.k.a. ENST00000443016.1, ENSG00000148429, NR_125732]
2)
Homo sapiens
SLC47A1 - Multidrug and
toxin
extrusion protein 1; Solute
transporter
for tetraethylammonium (TEA), 1-methyl-4- phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to
transport
paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes.
[a.k.a. SLC47A1-206, UPI00024D0D7D, ENST00000495425]
3)
Homo sapiens
SLC47A2 - Multidrug and
toxin
extrusion protein 2; Solute
transporter
for tetraethylammonium (TEA), 1-methyl-4- phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
[a.k.a. Q8IV44, MATE-2, NM_001256663]
4)
Homo sapiens
ARL4C - ADP-ribosylation factor-like protein 4C; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase- activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera
toxin
catalytic subunit. May be involved in
transport
between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in th [...]
[a.k.a. R-HSA-162582, ADP ribosylation factor like GTPase 4C, CAE30323.1]
5)
Homo sapiens
ABCG2 - Broad substrate specificity ATP-binding cassette
transporter
ABCG2; Broad substrate specificity ATP-dependent
transporter
of the ATP-binding cassette (ABC) family that actively extrudes a wide variety of physiological compounds, dietary
toxins
and xenobiotics from cells. Involved in porphyrin homeostasis, mediating the export of protoporphyrin IX (PPIX) from both mitochondria to cytosol and cytosol to extracellular space, it also functions in the cellular export of heme. Also mediates the efflux of sphingosine-1-P from cells. Acts as a urate exporter functioning in both renal and extra [...]
[a.k.a. ADO95123.1, ADO95120.1, NP_001335914]
6)
Mus musculus
Usp6nl - USP6 N-terminal-like protein; Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde
transport
from the endocytic pathway to the Golgi apparatus. Involved in the
transport
of Shiga
toxin
from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex (By similarity).
[a.k.a. ENSMUSP00000110587, XM_011238992, NP_852064.2]
7)
Mus musculus
Slc47a1 - Multidrug and
toxin
extrusion protein 1; Solute
transporter
for tetraethylammonium (TEA), 1-methyl-4- phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to
transport
paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membran [...]
[a.k.a. 1300013J15Rik, ENSMUSP00000010267, XP_006534058.1]
8)
Mus musculus
Slc47a2 - Multidrug and
toxin
extrusion protein 2; Solute
transporter
for tetraethylammonium (TEA), cimetidine, choline, procainamide, cimetidine, quinidine, guanidine, N- methylnicotinamide (NMN). Responsible for the secretion of cationic drugs across the brush border membranes; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
[a.k.a. MATE-2, UPI0000470565, ENSMUST00000093029]
9)
Mus musculus
Arl4c - ADP-ribosylation factor-like protein 4C; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase- activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera
toxin
catalytic subunit. May be involved in
transport
between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in th [...]
[a.k.a. Arl4c-202, ENSMUST00000187810.1, BAC37900.1]
10)
Mus musculus
Abcg2 - Broad substrate specificity ATP-binding cassette
transporter
ABCG2; Broad substrate specificity ATP-dependent
transporter
of the ATP-binding cassette (ABC) family that actively extrudes a wide variety of physiological compounds, dietary
toxins
and xenobiotics from cells. Involved in porphyrin homeostasis, mediating the export of protoporphyrin IX (PPIX) from both mitochondria to cytosol and cytosol to extracellular space, it also functions in the cellular export of heme. Also mediates the efflux of sphingosine-1-P from cells (By similarity). Acts as a urate exporter functioning in both [...]
[a.k.a. XP_006506213.1, Abcg2-209, XP_030111262.1]
11)
Caenorhabditis elegans
ttm-1 - Zinc
transporter
ttm-1; Promotes excretion of zinc from intestinal cells into the intestinal lumen in response to increased dietary zinc. Involved in cadmium resistance, possibly by promoting its
transport
from cells. Involved in resistance to B.thuringiensis pore-forming
toxin
Cry5B downstream of the sek-1 and pmk-1 MAPK kinase pathway.
[a.k.a. Y39E4A.2b, Y39E4A.2a.1, UPI00000821D3]
12)
Saccharomyces cerevisiae
YDR338C - Uncharacterized
transporter
YDR338C; Putative protein of unknown function; member of the multi-drug and
toxin
extrusion (MATE) family of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily.
[a.k.a. UPI000013A825, NP_010625, YDR338C_mRNA]
13)
Saccharomyces cerevisiae
IWR1 - RNA polymerase II nuclear localization protein IWR1; RNA polymerase II
transport
factor, conserved from yeast to humans; also has a role in
transporting
RNA polymerase III into the nucleus; interacts with most of the RNAP II subunits; nucleo-cytoplasmic shuttling protein; deletion causes hypersensitivity to K1 killer
toxin
; protein increases in abundance and relocalizes from nucleus to cytoplasm upon DNA replication stress.
[a.k.a. YDL115C, Q07532, NP_010168]
14)
Saccharomyces cerevisiae
SPF1 - Manganese-
transporting
ATPase 1; P-type ATPase, ion
transporter
of the ER membrane; required to maintain normal lipid composition of intracellular compartments and proper targeting of mitochondrial outer membrane tail-anchored proteins; involved in ER function and Ca2+ homeostasis; required for regulating Hmg2p degradation; confers sensitivity to a killer
toxin
(SMKT) produced by Pichia farinosa KK1.
[a.k.a. YEL031W, UPI0000052E71, NM_001178846]
15)
Escherichia coli K12
ghoS - Antitoxin of GhoTS
toxin
-antitoxin pair; Antitoxin component of a type V
toxin
-antitoxin (TA) system. Neutralizes the toxic effects of
toxin
GhoT by digesting ghoT transcripts in a sequence-specific manner. In concert with GhoT is involved in reducing cell growth during antibacterial stress. Overexpression leads to transcript level reduction of 20 other mRNAs involved in purine or pyrimidine synthesis and
transport
. Not seen to bind its own promoter DNA.
[a.k.a. AAC77089.1, b4128, yjdK]
16)
Acetobacter nitrogenifigens
GCA_000429165_02729 - Unannotated protein.
[a.k.a. GCA_000429165_02729, unannotated protein,
Toxin transporter
]
17)
Pseudomonas aeruginosa
PA4143 - Probable
toxin
transporter
; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
[a.k.a. AAG07530.1, Probable toxin transporter,
Toxin transporter
]
18)
Calothrix sp. PCC6303
AFZ04128.1 - Type I secretion system ATPase; PFAM: ABC
transporter
; Peptidase C39 family; ABC
transporter
transmembrane region; TIGRFAM: type I secretion system ABC
transporter
, HlyB family; COGs: COG2274 ABC-type bacteriocin/lantibiotic exporter contain an N-terminal double-glycine peptidase domain; InterPro IPR003593:IPR001140:IPR003439:IPR010132; KEGG: ana:alr1614
toxin
secretion ABC
transporter
ATP-binding protein; PFAM: ABC
transporter
-like; ABC
transporter
, transmembrane domain; PRIAM: Peptide-
transporting
ATPase; SMART: ATPase, AAA+ type, core; SPTR:
Toxin
secretion ABC
transporter
ATP-bindi [...]
[a.k.a. Cal6303_5242, Type I secretion system ATPase, 3.6.3.43]
19)
Nostoc sp. PCC7107
AFY45893.1 - Cyclic nucleotide-binding protein; TIGRFAM: type I secretion system ABC
transporter
, HlyB family; COGs: COG2274 ABC-type bacteriocin/lantibiotic exporter contain an N-terminal double-glycine peptidase domain; InterProIPR003593:IPR010132:IPR005074:IPR001140:IPR 003439; KEGG: ana:alr1614
toxin
secretion ABC
transporter
ATP-binding protein; PFAM: ABC
transporter
-like; ABC
transporter
, transmembrane domain; Peptidase C39, bacteriocin processing; PRIAM: Peptide-
transporting
ATPase; SMART: ATPase, AAA+ type, core; SPTR:
Toxin
secretion ABC
transporter
ATP-binding protein; TIGRFAM: ATPase, ty [...]
[a.k.a. Nos7107_5410, 3.6.3.43, K9QKK1_9NOSO]
20)
Rubinisphaera brasiliensis
ADY61963.1 - Xenobiotic-
transporting
ATPase; COGs: COG2274 ABC-type bacteriocin/lantibiotic exporter contain an N-terminal double-glycine peptidase domain; KEGG: psl:Psta_2756 ABC
transporter
related protein; PRIAM: Xenobiotic-
transporting
ATPase; SPTR: Probable
toxin
secretion ABC
transporter
ATP-binding protein; PFAM: ABC
transporter
transmembrane region.
[a.k.a. Plabr_4390, Xenobiotic-transporting ATPase, ADY61963]
409 matches
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